Modified Moving Average T-wave alternans cutpoints

Modified moving average analysis of T-wave alternans to predict ventricular fibrillation with high accuracy.

T-wave alternans is a marker of cardiac electrical instability with the potential for arrhythmia risk stratification. The modified moving average method was developed to measure alternans in settings with artifacts, noise, and nonstationary data. Algorithms were developed and performance characteristics were validated with simulated electrocardiograms (ECGs). Experimental laboratory ECGs with d...

Malignant T-wave alternans.

A36-year-old woman was referred after her son had syncopal episodes associated with a markedly prolonged QT interval, which was treated with b-blockers and a subsequent pacemaker. The mother had a history of “seizures” as a child that had been treated with various medications, which did not appear to affect her events. She continued to have episodes 2 to 3 times a year, and witnesses said she w...

Drug-induced T wave alternans.

Current Developments in Microvolt T-wave Alternans

Microvolt T-wave alternans (MTWA), the beat-to-beat fluctuation in T wave amplitude and morphology, is closely linked to vulnerability to ventricular arrhythmias in various experimental and clinical conditions. Clinically, MTWA is most commonly measured using the spectral method, although non-spectral methods for its assessment from ambulatory electrocardiographical recordings also have been de...

T-wave alternans and intraventricular conduction delays.

ross-sections, additional special factors, such as discontinuation of ntiplatelet therapy, antiplatelet resistance, intrinsic thrombogeicity, or coronary flow problems might trigger the development f LST. In comparison with previous data of 3-month follow-up (paients n 21, struts n 4,545) (3), thickness of NIH in the 2-year ollow-up group was greater than that in the 3-month follow-up roup (71 ...